Immunotherapy of food allergy: what is effective?

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Immunotherapy of food allergy: what is effective?

Allergic asthma as a complex outcome of pathogenic immunological, cellular and functional modifications of the airways is initiated by allergic reactions as a response mostly to inhalant allergens. Dysregulation of innate and adaptive immune functions contribute to the pathogenesis of the disease. A hallmark is the development of a Th2-driven inflammatory response in the airways. The underlying...

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Immunotherapy of food allergy: what is effective?

Food-induced anaphylaxis is the single leading cause of anaphylaxis seen in emergency departments. Consequently, a number of therapeutic strategies to treat food allergies are being pursued. Two non-allergen-specific therapies have been investigated in man: monoclonal anti-human IgE antibodies and a Chinese herbal formulation, FAHF-2. A trial with HU-901 anti-IgE was shown to raise the threshol...

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Immunotherapy for food allergy.

Although the current standard care for patients with food allergy is based on avoidance of the trigger foods with hope of possible gain of tolerance, increasing number of studies have shown that oral immunotherapy is a promising approach. Understanding the transcutaneous sensitization and oral immune tolerance to food antigens has shifted focus of treatment and prevention. However, more studies...

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Oral Immunotherapy for Food Allergy.

Food allergy is a potentially life-threatening condition with no approved therapies apart from avoidance and injectable epinephrine for treatment of acute allergic reactions. Oral immunotherapy (OIT) is an experimental treatment in which patients consume gradually increasing quantities of the food to which they are allergic in an attempt to induce some level of desensitization. While desensitiz...

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Oral Immunotherapy for Food Allergy

Food allergy is a potentially life-threatening condition with no approved therapies apart from avoidance and injectable epinephrine for treatment of acute allergic reactions. Oral immunotherapy (OIT) is an experimental treatment in which patients consume gradually increasing quantities of the food to which they are allergic in an attempt to induce some level of desensitization. While desensitiz...

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ژورنال

عنوان ژورنال: Clinical and Translational Allergy

سال: 2011

ISSN: 2045-7022

DOI: 10.1186/2045-7022-1-s1-s67